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By the uptake of this high molecular weight carbohydrate so quickly, WMS is driven into the muscle cells and muscle glycogen is quickly replenishedthrough anabolic stimulation of skeletal muscle. As a consequence of this rapid metabolism, it is often referred to as the rapid glycogen replenishing process. L-Carnitine Metabolic Significance, Muscle Glycogen Synthesis, and Muscle Adaptation L-Carnitine is released by mitochondria as a result of an increase in NADH and increased carnitine catabolism, by using ATP as an energy source. L-Carnitine is able to directly stimulate the energy production of the muscle, via the increase in phosphocreatine [21] (Figure 2) [22]. The main role of carnitine in muscle metabolism has been noted previously, [23] [24] Cellular uptake of L-Carnitine – Carnitine Transport – ATP Production Figure 2: The rate of L-carnitine uptake and its importance for muscle physiology. This is the time when L-carnitine stores are maximal, and where muscle glycogen is the substrate for energy production. Carnitine is used both directly by the muscles cell for energy production or indirectly for glycogen synthesis. [24] At the rate that mitochondria are pumping L-carnitine into the muscle cell, ATP production is up to 30 times higher than at rest. The ATP produced at the rate of 40 ATP/kg is the ATP that the mitochondria need to pump out at the rate of 1 ATP/kg per minute, and so requires the ATP/g carnitine ratio of 3 ATP/g carnitine. The ATP/g carnitine ratio increases dramatically when mitochondria are pumping into the larger muscle fibers from the smaller muscle fibers, which results in a fast rate of ATP production. This explains as well as the rapid increase in muscle glycogen levels during a workout and the quick response of muscle protein synthesis during exercise (Figure 2). L-Carnitine Metabolism – Anabolic Significance When skeletal muscle is being stimulated by the aerobic glycolysis and lactate re-uptake of the ingested carbohydrates, anabolic signals are being transmitted from the brain to the muscles cell. Muscle is an anabolic muscle tissue, and during this anabolic response, the mitochondria must be fully utilized for energy production. The uptake of L-carnitine has been shown to be anabolic and to lead to the stimulation of glycogen synthesis Similar articles:

Gentec anabolic factor x9 side effects, anabolic steroids for sale bitcoin
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